Which two organs are associated with immune disorders?

The correct association of lung and spleen with immune disorders stems from the recognized roles both organs play in the immune system. The lungs are critical as they are constantly exposed to environmental pathogens and play a key role in respiratory immunity. They contain immune cells such as macrophages and lymphocytes that help filter out pathogens and prevent infections. Disorders such as asthma, chronic obstructive pulmonary disease, and pneumonia highlight the lungs' involvement with immune function.

The spleen is often referred to as a blood filter and is integral to the immune response. It is responsible for producing and storing immune cells, particularly lymphocytes and macrophages, and plays a key role in clearing bloodborne pathogens and dead cells. Thus, any dysfunction or disorder affecting the spleen can directly impact the body’s ability to mount an immune response, leading to increased susceptibility to infections and other immune-related conditions.

While other options mention various organ combinations, they do not have the same level of direct involvement with immune disorders concerning recognized medical literature and practice. Therefore, the lung and spleen are indeed the organs most correlated with immune dysfunctions and disorders.